What's in the "New & Improved" modeRNA Boosters compared with their MSDS?
Or should the question be, what's with all of the "NO DATA AVAILABLE" in every chemical?
With the announcement from our alleged Top Doc, Dr. Tam(pon) earlier, I decided to get some answers from our "trusty" health agencies here in Cana-dope..
My questions:
1. What were the trial identifier #'s for the recent modeRNA booster shots?
2. Were they conducted in cana-dope?
3. If they were, how many canadians were enrolled?
4. How long were the trials?
5. What were the safety signals?
6. If there were trials conducted in Cana-duh, which phases were completed?
The answers from PHAC, Health Canadope, Health BC were very revealing.. They had NOTHING!!!!!
I, however, had. everything and kept those pricks on the phone for at. least 4 hours and they all got schooled.. :)
So, I called the Office of Clinical Trials but after 6 rings the line is disconnected with no option for voicemail..
My last call was to Research Ethics Board (REB) as I gained an ally back in late 2021 who, not only agreed with me but is doing everything possible to help with on my quest.. Oh, this person is also a manager with a PhD so no peons and NO I WILL NOT PROVIDE THE NAME AS I WANT THIS PERSON TO KEEP THEIR JOB!
We were talking about the latest round of BS, the lack of human trial data, safety signals, etc. which got me looking at Health Canada's website on the "new & improved" BOOSTER.. lol..
Oh boy..
Here’s the source link from Health Cana-duh’s website - https://www.canada.ca/en/health-canada/services/drugs-health-products/covid19-industry/drugs-vaccines-treatments/vaccines/moderna.html
Clinical trials showed that beginning 2 weeks after the second dose, the Moderna Spikevax® COVID vaccine was:
94.1% effective in protecting trial participants aged 18 and above against COVID-19
100% effective in trial participants 12 to 17 years old
as effective in trial participants 6 to 11 years old as in young adults (18 to 25 years old)
37% effective in trial participants 2 to 5 years old
51% effective in trial participants 6 to 23 months old
Notice the low "efficacy" in the kids (6 months to 5 years old)? Yet, they want to still push these on your kids? Um. No.
It gets worse. Further down the page I stumbled upon..
"Mixed-dose schedules
A different vaccine may be offered for your second dose. For example, you may have received Pfizer-BioNTech Comirnaty® as your first dose and be offered Moderna Spikevax® as your second. This is known as a mixed vaccine series.
The National Advisory Committee on Immunization (NACI) recommends an mRNA vaccine (Pfizer-BioNTech Comirnaty® or Moderna Spikevax®) should be offered for your second dose."
Um. THERE ARE NO STUDIES ON MIX AND MATCH AND BOTH PFIZZZZEERRR. & MODERNA MENTIONED THIS IN THEIR CLINICAL TRIALS AND PMA'S..
What about the ingredients? NON-mRNA
LIPIDS
DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine)
Lipid SM-102
PEG2000-DMG (1,2-dimyristoyl-rac-glycerol,methoxy-polyethyleneglycol)
Cholesterol
BUFFERS & SALTS
Acetic acid
Sodium acetate trihydrate
Sucrose
Trometamol
Trometamol hydrochloride
Water for injection
So let’s see how these chemicals look like compared to their predecessors. This time I’m assembling it alphabetically..
ACETIC ACID
Recommended Use - Laboratory chemicals.
Uses advised against - Food, drug, pesticide or biocidal product use.”
Label Elements
Signal Word - Danger
Hazard Statements - Flammable liquid and vapor
Causes severe skin burns and eye damage
Engineering Measures Use only under a chemical fume hood. Use explosion-proof electrical/ventilating/lighting equipment. Ensure that eyewash stations and safety showers are close to the workstation location. Ensure adequate ventilation, especially in confined areas.
11. Toxicological information
Irritation - Causes severe burns by all exposure routes
Sensitization- No information available
Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.
IARC NTP ACGIH OSHA Mexico
Not listed Not listed Not listed Not listed Not listed
Mutagenic Effects Not mutagenic in AMES Test
Reproductive Effects No information available.
Developmental Effects No information available.
Teratogenicity No information available.
STOT - single exposure None known
STOT - repeated exposure None known
Aspiration hazard - No information available
Symptoms / effects,both acute and delayed
Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting
Endocrine Disruptor Information - No information available
Other Adverse Effects The toxicological properties have not been fully investigated.
12. Ecological information
Ecotoxicity - Do not empty into drains.
Bioaccumulation/ Accumulation - No information available.
SOURCE - FISHER SCI . Original publish date? 2009. Last revision date? Dec 26, 2021. Total Revisions? 6
Well, the above sure looks safe to me.. So glad they oped to keep this one in the mix with all of the “No information available” sections.. What could possibly go wrong? :(
CHOLESTEROL
For this one, I’m going to use to different MSDS sheets as Fischer Sci (who also was one of the big dogs in the RT-PCR sweepstakes is up to something with this one)
Thermo Fisher Scientific
Recommended Use - Laboratory chemicals.
Uses advised against - Food, drug, pesticide or biocidal product use.
2. Hazard(s) identification
This chemical is not considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)
WAIT WHAT? Hmm.. something stinks here.. let’s see what CHEMICAL BOOK HAS TO SAY..
SECTION 2: Hazards identification
GHS Label elements, including precautionary statements
Symbol(GHS)
Signal word - Danger
Precautionary statements
P201 Obtain special instructions before use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Hazard statements
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H331 Toxic if inhaled
H336 May cause drowsiness or dizziness
H351 Suspected of causing cancer
H372 Causes damage to organs through prolonged or repeated exposure
HOUSTON WE HAVE A PROBLEM.
Let’s see what else Thero Fisher Scientific has to say for the rest of the doc.
SECTION 10: Stability and reactivity
Reactive Hazard None known, based on information available
11. Toxicological information
Toxicologically Synergistic Products - No information available
Irritation No information available
Sensitization No information available
Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.
IARC NTP ACGIH OSHA Mexico
Not listed Not listed Not listed Not listed Not listed
Mutagenic Effects - No information available.
Reproductive Effects - No information available.
Developmental Effects - No information available.
Teratogenicity - No information available.
STOT - single exposure - None known
STOT - repeated exposure - None known
Aspiration hazard - No information available
Symptoms / effects,both acute and delayed - No information available
Endocrine Disruptor Information - No information available
Other Adverse Effects - The toxicological properties have not been fully investigated.
Here’s what CHEMICALBOOK has to say about toxicity at the bottom of Sec 11.
”Toxicity - Present in all parts of the animal body; concentrated in spinal cord, brain, skin secretions, and gallstones. An unsaturated, unsaponifiable alcohol (m.p. 149℃). It is synthesized in the body from ethanoate units; its metabolism is regulated by a specific set of enzymes. It is the parent compound of many other steroids and its presence in high concentrations in the blood is suspected as being a contributory factor in cardiovascular disease.”
Back to Fisher Sci’s section
12. Ecological information
Ecotoxicity - Do not empty into drains.
Persistence and Degradability - No information available
Bioaccumulation/ Accumulation - No information available.
Mobility - No information available.
SOURCES - FISHER SCI (Revision Date 24-Dec-2021 Revision Number 4) & CHEMICALBOOK (2023-09-02 Revision Number:1)
DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine) (Lipids in the ancestral jabs but they added the DSPC anagram)
Recommended use of the chemical and restrictions on use - For research use only. Not intended for diagnostic or therapeutic use.
11. TOXICOLOGICAL INFORMATION
Information on likely routes of exposure
Inhalation - No data available.
Eye contact - No data available.
Skin Contact - No data available.
Ingestion - No data available.
Information on toxicological effects
Symptoms - No information available.
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Chronic Toxicity No information available.
Numerical measures of toxicity - Product Information
Unknown acute toxicity 100% of the mixture consists of ingredient(s) of unknown toxicity
12. ECOLOGICAL INFORMATION
Ecotoxicity - May cause long lasting harmful effects to aquatic life
100% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
Persistence and degradability - No information available.
Bioaccumulation - No information available.
Mobility - No information available.
SOURCE - Santa Cruz Biotechnology Inc (May 2, 2017)
Lipid SM-102
Application of the substance / the mixture
This product is for research use - Not for human or veterinary diagnostic or therapeutic use.
2 Hazard(s) identification
· Classification of the substance or mixture (sorry I couldn’t add the little icons)
Flam. Liq. 2 H225 - Highly flammable liquid and vapor.
Acute Tox. 4 H302 - Harmful if swallowed.
Skin Irrit. 2 H315 - Causes skin irritation.
Eye Irrit. 2A H319 - Causes serious eye irritation.
Signal word - Danger
Hazard statements
H225 Highly flammable liquid and vapor.
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
· Precautionary statements
P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 If swallowed: Call a poison center/doctor if you feel unwell.
P330 Rinse mouth.
P321 Specific treatment (see on this label).
P303+P361+P353 If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313 If skin irritation occurs: Get medical advice/attention.
P362+P364 Take off contaminated clothing and wash it before reuse.
P337+P313 If eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use CO2, powder or water spray to extinguish.
P501 Dispose of contents/container in accordance with local/regional/national/international regulations.
3 Composition/information on ingredients
· Chemical characterization: Mixtures
· Description: Mixture of the substances listed below with nonhazardous additions.
· Dangerous components:
CAS: 64-17-5 - RTECS: KQ6300000 ethanol 90.0%
CAS: 2089251-47-6 SM-102 10.0%
Wait a second. There is ETHANOL PRESENT IN THIS INGREDIENT?
10 Stability and reactivity
· Reactivity - No further relevant information available.
· Chemical stability
· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
· Possibility of hazardous reactions No dangerous reactions known.
· Conditions to avoid No further relevant information available.
· Incompatible materials: No further relevant information available.
· Hazardous decomposition products: No dangerous decomposition products known.
11 Toxicological information
LD/LC50 values that are relevant for classification:
ATE (Acute Toxicity Estimate)
Oral LD50 5,000 mg/kg
64-17-5 ethanol
Oral TDLO 1.14 ml/kg (man)
LD50 7,060 mg/kg (rat)
TDLO 650 (man)
Dermal. LD50 40,000 mg/kg (rat)
Inhalative TCLO 1,800 (hmn)
LC50 10 h - 20,000 mg/m³ (rat)
LD50 Inhalation TCLO 1,800 mg/m³/30m (hmn)
Irritation of skin TDLO 1,800 mg/kg (wmn)
· Primary irritant effect:
· on the skin: Irritant to skin and mucous membranes.
· on the eye: Irritating effect.
· Sensitization: No sensitizing effects known.
· Additional toxicological information:
The product shows the following dangers according to internally approved calculation methods for preparations:
Harmful
Irritant
· Carcinogenic categories
IARC (International Agency for Research on Cancer) 64-17-5 ethanol
SOURCE - CAYMEN CHEMICAL (Printing date 06/07/2022)
PEG2000-DMG (1,2-dimyristoyl-rac-glycerol,methoxy-polyethyleneglycol)
PEG-lipid is used to control the particle size and act as a steric barrier to prevent aggregation during storage.
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses: Laboratory chemicals, Synthesis of substances.
10. STABILITY AND REACTIVITY
10.1 Reactivity - No data available.
10.2 Chemical stability - Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions - No data available.
10.4 Conditions to avoid - No data available.
10.5 Incompatible materials - Strong acids/alkalis, strong oxidising/reducing agents.
10.6 Hazardous decomposition products - Under fire conditions, may decompose and emit toxic fumes.
Other decomposition products - no data available
12. ECOLOGICAL INFORMATION
12.1 Toxicity - No data available.
12.2 Persistence and degradability - No data available.
12.3 Bioaccumlative potential - No data available.
12.4 Mobility in soil - No data available.
12.5 Results of PBT and vPvB assessment - PBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted. (WHY NOT?)
12.6 Other adverse effects - No data available.
Source - Med Chem Express (Revision Date: Apr.-20-2023)
SODIUM ACETATE TRIHYDRATE (commonly used in heat packs)
1.2. RECOMMENDED USE AND RESTRICTIONS ON USE:
USE OF THE SUBSTANCE/MIXTURE: FOR LABORATORY AND MANUFACTURING USE ONLY.
RECOMMENDED USE: LABORATORY CHEMICALS
RESTRICTIONS ON USE: NOT FOR FOOD, DRUG OR HOUSEHOLD USE
SECTION 10: STABILITY AND REACTIVITY
10.1. REACTIVITY: NO ADDITIONAL INFORMATION AVAILABLE
10.3. POSSIBILITY OF HAZARDOUS REACTIONS: NOT ESTABLISHED.
10.4. CONDITIONS TO AVOID: DIRECT SUNLIGHT. EXTREMELY HIGH OR LOW TEMPERATURES.
10.5. INCOMPATIBLE MATERIALS: STRONG ACIDS. STRONG BASES. STRONG OXIDIZERS.
10.6. HAZARDOUS DECOMPOSITION PRODUCTS:
FUME. CARBON MONOXIDE. CARBON DIOXIDE.
SECTION 11: TOXICOLOGICAL INFORMATION
11.1. INFORMATION ON TOXICOLOGICAL EFFECTS:
ACUTE TOXICITY (ORAL): NOT CLASSIFIED
ACUTE TOXICITY (DERMAL): NOT CLASSIFIED
ACUTE TOXICITY (INHALATION): NOT CLASSIFIED
SKIN CORROSION/IRRITATION: NOT CLASSIFIED
PH: 8.9 1M SOLUTION
SERIOUS EYE DAMAGE/IRRITATION: NOT CLASSIFIED
PH: 8.9 1M SOLUTION
RESPIRATORY OR SKIN SENSITIZATION: NOT CLASSIFIED
GERM CELL MUTAGENICITY: NOT CLASSIFIED
CARCINOGENICITY: NOT CLASSIFIED
REPRODUCTIVE TOXICITY: NOT CLASSIFIED
STOT-SINGLE EXPOSURE: NOT CLASSIFIED
STOT-REPEATED EXPOSURE: NOT CLASSIFIED
ASPIRATION HAZARD: NOT CLASSIFIED
VISCOSITY, KINEMATIC: NO DATA AVAILABLE
LIKELY ROUTES OF EXPOSURE: INHALATION. SKIN AND EYE CONTACT.
POTENTIAL ADVERSE HUMAN HEALTH EFFECTS AND SYMPTOMS:
BASED ON AVAILABLE DATA, THE CLASSIFICATION CRITERIA ARE NOT MET (OH BOY :( )
SECTION 12: ECOLOGICAL INFORMATION
12.1. TOXICITY: NO ADDITIONAL INFORMATION AVAILABLE
12.2. PERSISTENCE AND DEGRADABILITY:
SODIUM ACETATE, TRIHYDRATE (6131-90-4):
PERSISTENCE AND DEGRADABILITY: NOT ESTABLISHED.
12.3. BIOACCUMULATIVE POTENTIAL:
SODIUM ACETATE, TRIHYDRATE (6131-90-4):
BIOACCUMULATIVE POTENTIAL: NOT ESTABLISHED.
12.4. MOBILITY IN SOIL: NO ADDITIONAL INFORMATION AVAILABLE
12.5. OTHER ADVERSE EFFECTS:
OTHER INFORMATION: AVOID RELEASE TO THE ENVIRONMENT.
Source - Grainger (ISSUE DATE: 12/10/2013 REVISION DATE: 11/24/2020)
Sorry for all of the caps. Sadly, this is how it presented when I copied it. :(
However, what does CHEMICAL BOOK have to say about this one?
Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses - For R&D use only. Not for medicinal, household or other use.
SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity LD50 Oral - Rat - 3.530 mg/kg Remarks: (anhydrous substance) (RTECS)
LC50 Inhalation - Rat - male and female - 4 h - > 5,6 mg/l (OECD Test Guideline 403) Remarks: (anhydrous substance)
LD50 Dermal - Rabbit - female - > 20.000 mg/kg (OECD Test Guideline 402)
Remarks: (anhydrous substance)
Skin corrosion/irritation
Respiratory or skin sensitization - No data available
Germ cell mutagenicity - No data available
Reproductive toxicity No data available
Specific target organ toxicity - single exposure - No data available
Specific target organ toxicity - repeated exposure - No data available
Aspiration hazard - No data available
Toxicity - LD50 orally in Rabbit: 3530 mg/kg LD50 dermal Rabbit > 10000 mg/kg
Source - CHEMICAL BOOK (Revision Date:2023-05-06 Revision Number:1)
SUCROSE
In my original MDSD/Ingredient Substack I didn’t really spend much time on this one as it’s supposed to be sugar. Big mistake. Read on.
Relevant identified uses: For R&D use only. Not for medicinal, household or other use. (SUGAR, REALLY? ;) )
Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 29.700 mg/kg
Remarks: Behavioral: Somnolence (general depressed activity). Cyanosis
Diarrhea, Inhalation
Skin corrosion/irritation - No data available
Serious eye damage/eye irritation- No data available
Respiratory or skin sensitization- No data available
Carcinogenicity - No data available
Reproductive toxicity - No data available
Specific target organ toxicity - single exposure - No data available
Specific target organ toxicity - repeated exposure - No data available
Aspiration hazard - No data available
Toxicity - LD50 orally in Rabbit: 29700 mg/kg (POOR BUNNIES)
SECTION 12: Ecological information
Toxicity - No data available
Persistence and degradability - No data available
Bioaccumulative potential - No data available
Mobility in soil - No data available
Source - CHEMICAL BOOK (Revision Date:2023-09-09Revision Number:1)
TROMETAMAL
1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses: For research use only, not for human or veterinary use.
10 STABILITY & REACTIVITY
10.1 Reactivity - No data available.
10.3 Possibility of hazardous reactions - No data available.
10.4 Conditions to avoid - No data available.
10.5 Incompatible materials - Strong acids/alkalis, strong oxidising/reducing agents. 10.6 Hazardous decomposition products - Under fire conditions, may decompose and emit toxic fumes.
Other decomposition products - no data available.
11 TOXICOLOGICAL INFORMATION
11.1 Information on toxicological effects - The toxicological effects of this product have not been thoroughly studied.
Carcinogenicity: NTP? No IARC Monographs? No OSHA Regulated? No ACGIH? No
SOURCE - ABMOLE (I HAVE NO IDEA WHEN THIS WAS CREATED)
(NOTE: When reviewing other MSDS sheets for Trometamol there are sections which have additional Toxicological Effects such as, Thermo Fisher Sci’s MSDS
Toxicologically Synergistic Products - No information available
Delayed and immediate effects as well as chronic effects from short and long-term exposure (EMPHASIS ADDED)
Irritation - No information available
Sensitization No information available
Mutagenic Effects- No information available
Reproductive Effects - No information available.
Developmental Effects - No information available.
Teratogenicity - No information available.
STOT - single exposure - None known
STOT - repeated exposure - None known
Aspiration hazard - No information available
Symptoms / effects,both acute and delayed - No information available
Endocrine Disruptor Information - No information available
Other Adverse Effects - The toxicological properties have not been fully investigated.
SOURCE - THERMO FISHER SCIENTIFIC (Creation Date 15-Dec-2011 Revision Date 24-Dec-2021 Revision Number 4)
TROMETAMOL HYDROCHLORIDE aka TRIS HYDROCHLORIDE
Recommended Use - Laboratory chemicals
Uses advised against - Food, drug, pesticide or biocidal product use
10. Stability and reactivity
Reactive Hazard - None known, based on information available
11. Toxicological information
Acute Toxicity
Product Information - No acute toxicity information is available for this product
Irritation - Irritating to eyes, respiratory system and skin
Sensitization No information available
Carcinogenicity - NO RESULTS (as per table).. Hmmmmm
Mutagenic Effects - No information available
Reproductive Effects - No information available.
Developmental Effects - No information available.
Teratogenicity - No information available.
STOT - single exposure - None known
STOT - repeated exposure - None known
Aspiration hazard - No information available
Symptoms / effects,both acute and delayed - No information available
Endocrine Disruptor Information - No information available
Other Adverse Effects - The toxicological properties have not been fully investigated.
SOURCE - THERMO FISHER SCIENTIFIC (Creation Date 26-Sep-2009 Revision Date 24-Dec-2021 Revision Number 7
So what are the chemical differences in the Lipids, Salts & Buffers compared to the ancestral shots for modeRNA? They added “DPSC” to the 1,2-distearoyl-sn-glycero-3-phosphocholine which I believe is the actual term for it & replaced Sodium Acetate with Sodium acetate “trihydrate”..
The “trihydrate” addition is the presence of water molecules (3 per formula unit), lower melting point and more soluble. Oh it can crystallize when exposed to heat which is why it’s used in heat packs in conjunction with Sodium Acetate..
Noted & shared .