If the boosters never worked on mice, how could they work on HUMANS?
Short answer? They can't..
You know what I despise? Proof that a certain product causes harm and other nastiness.. Yup.. Hate it as no one cares about it.. The masses don't give a crap. The media are too chicken shit to report on it. The gov't does everything in its power to bury it under the rug. The alleged health "experts" try and find a way to spin or discredit it or even ignore it..
However, with my very light sarcasm aside, it's time for a reminder no the alleged/mislabelled product, they call "The Booster".
From Dec 20, 2022.
"Extended SARS-CoV-2 RBD booster vaccination induces humoral and cellular immune tolerance in mice"
"The repetitive applications of vaccine boosters have been brought up in face of continuous emergence of SARS-CoV-2 variants with neutralization escape mutations, but their protective efficacy and potential adverse effects remain largely unknown."
NOTE. of course their efficacy and potential AE's are largely unknown if you don't study them in the trials or study them ,find out that there are safety signals, etc.. Remember, THERE WERE NO HUMANS INVOLVED IN THE BOOSTER CLINICAL TRIALS!.. Shall I re-type this? Yet there are those who took the 1st round of shots continue to take them.
Why?
What are the benefits?
-You won't get sick? Nope. You still will.
- You won't get hospitalized? Nope. Still happens
- You won't wind up in the ICU? Nope.. You will with the potential of other issues triggered from the product you allowed to be injected into your deltoid muscle which was goes throughout your blood stream and organs and penetrates your blood barrier
- You won't die? Well, we all eventually die but this also exacerbates your chances of death..
These products are hurting your immune system and your body, in general and studies go back as early as April 2021
"Highlights
• IL-10 overproduction compromises NSC survival, leading to hippocampal neurogenesis reduction in adulthood.
• IL-10 overproduction results in spatial learning and memory impairment.
• IL-10 overproduction increases microglial CD200R expression and reduces microglial CX3CR1 expression in the hippocampus.
• Effects by IL-10 overproduction resemble those produced by physiological aging.
5. Conclusions
This work shows the importance of the microenvironment on microglial cells and their relationship with neurogenesis. Interestingly, we have demonstrated that chronic anti-inflammatory IL-10 overproduction has a similar effect to physiological aging on the hippocampus. Specifically, in transgenic animals and WT with normal aging, hippocampal neurogenesis and memory are impaired together with alterations in the microglia-neuron communication. Likely, IL-10 overexpression modifies microglial receptors involved in neuronal communication, resulting in reduced neurogenesis. This study emphasizes the variety of possibilities that a specific cytokine can exert depending on the moment and the time in which it is expressed. Thus, we describe new properties of IL-10 in hippocampal neurogenesis in vivo."
https://www.sciencedirect.com/science/article/pii/S0889159121006577
Back to the Dec study..
"Multiple vaccine boosters after the conventional vaccination course significantly decreased RBD-specific antibody titers and serum neutralizing efficacy against the Delta and Omicron variants, and profoundly impaired CD4+ and CD8+T cell activation and increased PD-1 and LAG-3 expressions in these T cells. Mechanistically, we confirmed that extended vaccination with RBD boosters overturned the protective immune memories by promoting adaptive immune tolerance. Our findings demonstrate potential risks with the continuous use of SARS-CoV-2 vaccine boosters, providing immediate implications for the global COVID-19 vaccination enhancement strategies."
- Boosters vs Primary series and not real "vaccines". Moreover, RBD's (receptor binding domains) are a key part of a virus located on its ‘spike’ domain that allows it to dock to body receptors to gain entry into cells and lead to infection. These are also the primary targets in the prevention and treatment of viral infections. These RBD's are turning on the body and attacking your immune system. The fact that the body initially accepts the synthetic self-assembling spike protein then turns on the spike once it realizes that it's an imposter is too late. The damage has been done and will continue to do as such to the point that you WILL wind in the hospital, ICU and potentially die quicker. :(
CD4 and CD8 are important for immunity protection and they are now impaired after the shots.. Don't forget. These shots don't promote/provide mucosal immunity which is paramount for fighting upper respiratory viruses, well the ones that they have proof of isolation/purification, of which SARS CoV-2 did either..
These shots are hurting your immune system and removing your antibodies. FACT. Therefore the manufactures and their paid govt and health shills are lying through their teeth..
The study authors are also hinting that the jabs are a risk and should be stopped based on my interpretation.
"Since late 2021, the SARS-CoV-2 Omicron variant has overtaken the global dominance and epidemiology studies have identified substantial levels of vaccine breakthrough infections and reinfections"
- No shit sherlock. These alleged 1st series of "vaccines" were allegedly developed for the alleged ancestral strain and NOT THE VARIANTS (delta, omnicron, etc).
"Accumulating evidence showed that the use of the first vaccine booster dose was safe and effective, and it could produce high titers of neutralizing antibodies with improved efficacy against Omicron variants "
- Like hell it was. If anything more people got sick, hospitalized, wound up in the ICU or died as a direct result of the rollout which I pointed out in one of my latest substack pieces -
"However, the serum protection after one booster vaccination was shown to decline with time, which again rendered the immunized individuals prone to continuous risk from newly emerged SARS-CoV-2 variants. Thus, the administration of a second booster vaccine or, possibly, routine vaccination with boosters was brought to light, for which scarce information was available. More information was needed to properly address relevant questions in the practical field of COVID-19 prophylaxis, such as the recommended condition for the use of additional booster vaccines, the suggested number of enhancement shots to be given and the potential adverse effects of continues administration of booster vaccines."
- Imagine my surprise? It never had any protection to begin with. Yet another fact.
"One of the major concerns associated with continuous immunization with booster vaccines is the relative limited response window of systematic immunity to the same stimuli. It has been reported that foreign antigen stimulation can induce immune tolerance, which is manifested as inability or low efficiency to produce antigen-specific antibodies and to activate effector T cells"
- Remember my point above when I mentioned that the fake spike tricks the body then attacks it? I hate being right.. ;)
"Presently, it is unclear whether extended administration of RBD vaccine boosters can re-establish protective immunity or is prone to induce immune tolerance."
- I beg to differ
"We found that the conventional immunization course could stimulate sustained levels of neutralizing antibodies and promote the antigen specific CD4+ and CD8+T cell reactivity. However, continued vaccination promoted the formation of a prominent adaptive immune tolerance and profoundly impaired the established immune response with the conventional course, evidenced by significant reductions in antigen specific antibody and T cell response, a loss of immune memory and form of immunosuppression micro-environment. Our findings demonstrated the potential risks associated with an extended vaccine booster course of SARS-CoV-2 vaccination, with immediate implications for the strategic use of homology booster vaccines."
- The 1st part of this is debatable but the rest is "statistically significant" enough to warrant a full stop.
"Results
Extended immunization did not enhance RBD specific antibody production in mice
"Extended immunization reduced serum neutralizing antibody responses"
"Extended immunization inhibited the production of RBD-specific memory B cells"
"Extended immunization suppressed the formation of the germinal center"
"Extended immunization inhibited the activation of CD4+T cell immune responses"
"Extended immunization inhibited CD8+ T cell-mediated immune response"
- So if it doesn't work in mice, how can it work in humans?
https://www.sciencedirect.com/science/article/pii/S2589004222017515